2. A REVIEW OF PHYTO-CHEMICAL CONSTITUENT AND PHARMACOLOGICAL ACTIVITY OF THUJA SPECIES
Traditional healthcare systems play an important role in our healthcare system. The villagers use this plant mainly for the treatment of various diseases. Thuja belongs to the family of cupressacae. This is commonly used in Ayurvedic medicine. There are five species in the thuja genus, three local to eastern Asia and two local to North America. Phylogenomic investigations resolved two sister sets, T. standishii- T. koraiensis and T. ocidentalis- T. sutchuenensis, with T. plicata sister to T. occidentalis-T. sutuenensis. This alternative system of medication is increasing expanding fame overall Thuja species are generally used as an antiviral, antibacterial, anti-cancer, anti-diabetic, anti-HIV, anti- fungal etc. Antiviral action and immunopharmacological action of Thuja, as stimulatory effects on cytokine and antibody production and also activate macrophages cells, have been tested in various in-vivo and in-vitro study. Thuja species have different chemical substances like thujone, isothujone, fenchone, sabines and ?-pinen. This review article provides comprehensive information on various useful and traditional medicinal properties of chemical composition and pharmacological activity of plants and their components.