1. DEVELOPMENT OF BENZIMIDAZOLE DERIVATIVES AS TARGET BASED ANTITUMOR DRUGS: AN OVERVIEW
Cancer (also being identified as neoplasm, proliferative activity or tumours), is a world-wide uncontrolled disease affecting almost every part of the world. Cancer can be defined as the excess of reproduction of targeted cells due to abnormality in action of the molecular function or in signal transmissions. Although, various of anticancer drugs were already marketed and in applicable. Most of the drugs identified does not have selective targeted actions which directly or indirectly affects the normal cells of the targeted area. This review surveyed and studied about various of novel synthesized anticancer active drugs targeting selective interacting sites of malignant cells like hCAs, tubulin protiens, Gal-1, EGFR, and so on.